Endocrine Abstracts

Aim: The work was initiated to study depression manifestations in patients with primary hyperparathyroidism.Materials and methods: Symptoms of anxiety and depression were assessed in 67 patients with primary hyperthyroidism aged from 16 to 30 years examined by means of Spielberger–Khanin’s test and Beck’s Depression Inventory.Problem of marginal psychoneurotic disturbances in patients with various somatic pathologies...

AimAssessment of surgery efficacy in patients with MTC.MethodsWe used DNA extracted from 53 patients with MTC. All samples were subjected to PCR. Radio-immunological examination, serum CT measurement was performed by means of commercially available kit RIA DCL-1200. Basal calcitonin (CT) levels higher than 100 picograms per ml and the stimulated CT levels are accepted as pathological and typical of MTC.<p...

Calcium is an important part of bone tissue. Appropriate calcium intake is necessary for maintenance of healthy bones. In accordance with international recommendations, people at age from 19 to 50 have to consume 1000 mg of calcium daily. For the measurement of the level of the calcium intake we develop worksheet, which contains denomination of different foods and products, with their calcium content (mg), which usually are consumed. Purpose: Measurement of calcium intake by s...

Objective: To determine the incidence of thyroid dysfunction in a cohort of patients started on amiodarone therapy at a cardiac clinic in Tashkent, Uzbekistan, which is believed to be an iodine- deficient area.Methods: Pharmacy records were used to obtain the names of patients who received amiodarone between 2006 and 2009.Results: The original sample size was 96; 3 patients were excluded to incomplete data and data analysis was com...

Aim: To evaluate influence of cabergoline on LAO and BAS processes in treatment of patients with NFPA.Materials and methods: We included 64 patients with NFPA in the study. Mean age was 43.6±3.84 years (range 30–55 years). Of 64 patients 26 (40.6%) were men and 38 (59.4%) were women. Duration of the disease from diagnosis based on MRI constituted 1–15 years. Severity criteria used in the evaluation were LH, FSH and prolactin (PRL) growth a...

Introduction: Iodine deficiency disorders are considered as the most wide spread non infectious diseases of the humanity. Uzbekistan is in the zone of the severe iodine deficiency (ID). According to epidemiologic studies performed in 1998 endemic goiter (EG) prevalence was 80% whereas urinary iodine was <10 μg/l. In May, 2007 Uzbek government legislated the Salt Iodization Law and in 2009 ID evaluation was performed in the Uzbekistan using sentinel approach.<p cla...

Actuality: According to WHO, 36% of patients with type 2 diabetes mellitus (T2DM) suffer from obstructive sleep apnoe syndrome (OSAS), which is one of global problems of modern medicine. International classification of sleep disorders identified that 24% of men and 9% of women with T2DM observe symptoms of OSAS. Sleep apnea has a negative effect on the function of the beta cells of the pancreas and insulin sensitivity. Obstructive sleep apnea has a negative impact on the quali...

Aim: To study character of macrovascular complications in combination of diabetes mellitus (DM) and diabetes insipidus (DI).Materials and methods: Within the period from 2006 to 2010, we examined 2208 cases of DI among them 106 DM–DI combinations. The patients had their endocrine and neurologic statuses assessed with blood and urine density investigation, including complete urinalysis and Zimnitskyi urine count, RIA and measurement of pituitary horm...

This research was designed to estimate effectiveness and safety of Lindaxa in treatment of obesity associated with IGT and arterial hypertension. Thus, 20 women (mean age 37.9 years-old) were treated with complex therapy including traditional therapy (diet, physical exercises, dhydration, metabolic and symptomatic treatment) including Lindaxa with dosage of 10–15 mg/day once daily during 6 months. Physical exercises were determined individually according to BMI and metabo...

Aim: To study the effectiveness of metformin in treatment of polycystic ovaries syndrome (PCOS) in women of birthing age.Materials and methods: We followed 31 women with PCOS. Mean age of patients was 29.8 years old. All patients were evaluated for hormones levels (LH, FSH, TSH, estradiol, progesterone, testosterone, prolactin, coritsole, free thyroxine, dehydroepiahndrostendione etc.), glucose tolerance test, lipids profile, uterus and ovaries ultrasono...